RNA-2006

CENTRO DE CIENCIAS DE BENASQUE


RNA-2006

2006, July 16-28



Monday, July 17
  • 10:30h
  • Welcome
     Lecture room.
  • 11:00h
  • Peter STADLER
     Lecture room
  • 18:00h
  • Organizational meeting.
     Lecture room

    Tuesday, July 18
    • 11:00h
    • RNA Structure Prediction, abstract shapes, representative structures, complete shapes probabiliies
       Robert Giegerich (coordinator)
        Structure clustering with centroids
       Ye Ding
        Locally optimal structures
       Peter Clote
        Structure prediction with force
       Ralf Bundschuh
        Classified dynamic programming
       Robert Giegerich
    • 18:00h
    • microRNA target precition
       Ye Ding (coordinator)
        RNAhybrid
       Robert Giegerich
        Thermodynamic structure of RNA hybrids
       Stephen Bernhart
        miRNA target prediction
       Erik van Nimwegen and Mihaela Zavolan
        FASTH: application to microRNA target prediction
       Michael Zuker
        Ponent role of target structure on microRNA function
       Ye Ding

      Wednesday, July 19
      • 11:00h
      • Special models for RNA secondary structure
         Dimitri Perchouvine (coordinator)
          Algorithms for RNA-RNA matching
         Dimitri Perchouvine
          Folding RNA with pseudoknots
         Jens Redder
          Asymtotic behaviour of equilibrium free energy per nucleotide for randomly generated sequences
         Peter Clote
          k-point mutants and k-superoptimal secondary structures
         Jerome Waldispuhl
      • 18:00h
      • RNA processing
         Steven Brenner (coordinator)
          NAG NAG and small exon variation
         Mihaela Zavolan
          Insertional RNA editing
         Ralf Bundschuh
          Ultraconserved nonsense
         Steven Brenner

        Thursday, July 20
        • 09:00h
        • RNA ontology - motifs
           Neocles Leontis, Steven Brenner, Francois Major
        • 11:00h
        • Generic structural RNA genefinders
           Stefan Washietl, Jakob Pedersen (coordinators)
            Methods based on energy directed consensus folding
           Stefan Washietl
            phylo-SCFG based structural RNA identification
           Jakob Pedersen
            Conserved strucutres in non-conserved sequences
           Elfar Torarinsson
            noncoding RNA detection using mfe (dynalign)
           Andrew Usilov
            Kernel function for RNA sequence analysis
           Yasubumi Sakakibara
            C elegans and noncoding RNAs
           Sean Eddy
        • 18:00h
        • Specific RNA genefinders
           Daniel Gautheret (coordinator)
            miRNA prediction using SVM classification. snoRNA prediction
           Jana Hertel
            What's and what's not a miRNA precursor?
           Daniel Gautheret
            Viral miRNA gene search
           Ye Ding
            A generic tool for specific genefinding
           Robert Giegerich
            viral miRNAs
           Mihaela Zavolan

          Friday, July 21
          • 11:00h
          • RNA alignments I (applications of the Sankoff algorithm)
             Rolf Backofen (coordinator)
              Local and global sequence/structure alignment and the Sankoff algorithm
             Rolf Backofen
              FOLDALIGN (a version of the Sankoff algorithm)
             Jan Gorodkin
              DYNALIGN
             Dave Mathews
              Simulfold: efficient co-estimation of phylogeny, alignment and common RNA structure including pseudoknots
             Irmtraud Meyer
          • 16:00h
          • Systematic dynamic programming (unauthorized talk)
             Robert Giegerich
          • 18:00h
          • RNA phylogeny and evolution
             Ian Holmes (coordinator)
              Conserved RNAs in mammals
             Mike Pheasent
              Environmental sequencing and phylogeny
             Rob Knight
              Phylo-grammars and PFOLD
             Bjarne Knudsen
              RNA decoder
             Irmi Meyer
              Tree transducers and Xrate
             Ian Holmes
              Jukes-Cantor with gaps
             Elena Rivas

            Monday, July 24
            • 11:00h
            • Three dimensional structure
               Eric Westhof (coordinator)
                Alignments
               Karine St-Onge
                3D search of motifs
               Craig Zirbel
            • 18:00h
            • RNA folding kinetics and energy landscapes
               Ivo Hofacker (coordinator)
                Sequences, structures, shapes and conformations
               Peter Schuster
                Barrier trees and dynamic landscapes
               Ivo Hofacker
                RNA kinetics: a webserver for RNA folding
               Dimitri Pervouchine
                Clusters and energy wells of suboptimals
               Ye Ding
                Translocation through nanopores
               Ralf Bundschuh
                Conformational change pathways
               Dave Mathews

              Tuesday, July 25
              • 11:00h
              • RNA ontology
                 Neocles Leontis (coordinator)
                  Why do we need an ontology for RNA?
                 Neocles Leontis
                  Ontology and multiple sequence alignments
                 Eric Westhof
                  Automating motif recognition alignment
                 Craig Zirbel
              • 17:00h
              • RNA alignments II
                 Jan Gorodkin (coordinator)
                  Complexity of RNA editing and alignment
                 Alain Denise
                  Different ways of locality
                 Rolf Backhofen
                  RNACAST
                 Jens Reeder
                  STRAL and Bralibase
                 Gerhard Steger
                  Folding profiles
                 Rune Lyngso
                  CONSAN: the sankoff algorithm with alignment constraints
                 Robin Dowell

                Wednesday, July 26
                • 11:00h
                • RNA homology
                   Paul Gardner (coordinator)
                    Introduction to profile HMMs and CMs
                   Sean Eddy
                    Speedups for CMs
                   Eric Nawrocki
                    Heuristics for faster annotation of noncoding RNA families
                   Zasha Weinberg
                    Benchmarking RNA homology search tools
                   Paul Gardner
                    RNA secondary structural alignment with conditional random fields
                   Kengo Sato
                    Hardware accelerated BLAST/Smith-Waterman
                   Bjarne Knudsen
                • 15:00h
                • RNA ontolgy - alignment
                   Neocles Leontis, Eric Westhof
                • 18:00h
                • RNA design
                   Anne Condon (coordinator)
                    Nucleic acid design: motivation, design criteria, and computational complexity
                   Anne Condon
                    SimilRNA - what does it mean for RNA designs to be similar?
                   Amanda Birmingham
                    Designing multistable RNA sequences
                   Ivo Hofacker
                    Design by evolution
                   Peter Schuster
                    Rational design of mRNA-targeting nucleases
                   Ye Ding

                  Thursday, July 27
                  • 11:00h
                  • RNA databases
                     Sam Griffith-Jones (coordinator)
                      What can and can't they do for us?
                     Sam Griffiths-Jones
                      (And panel discussants respond:)
                     Jakob P, Robin D, Paul G, Jens R, Eric W, Jan G
                  • 16:00h
                  • Stochastic multiple context-free grammar for RNA pseudoknot modeling (ad hoc talk)
                     Yuki Kato
                  • 18:00h
                  • Pragmatic tools for RNA analysis
                     Bjarne Knudsen (coordinator)
                      Software used for Rfam
                     Sam Griffiths-Jones
                      SARSE: Semi-Automated RNA Sequence Editor
                     Jan Gorodkin & Bjarne Knudsen
                      GenRGenS: Generalizing random sequences and structures
                     Alain Denise
                      Deep sequencing of Arabidopsis siRNAs and miRNAs
                     Vincent Moulton
                      MC-web
                     Francois Major
                      Should there be a contest for RNA 2D structure prediction (a la CASP)?
                     Eric Westhof